Born in Yerevan, Armenia, Sergey Khachatryan won First Prize at the VIII International Jean Sibelius Competition in Helsinki in 2000, becoming the youngest ever winner in the history of the competition. In 2005 he claimed First Prize at the Queen Elisabeth Competition in Brussels.

Highlights of this season include Sergey's residency at the BOZAR, Brussels which includes a pair of recitals and concert with Orchestre National de Belgique and Hugh Wolff. He also performs with the Netherlands Radio Philharmonic Orchestra with Stanislav Kochanovsky, Orchestra della Svizzera Italiana and Gulbenkian Orchestra with Lorenzo Viotti, Bamberger Symphoniker with Ludovic Morlot and Rotterdam Philharmonic with Valery Gergiev, as well as at the Teatro alla Scala Milan under Myung-Whun Chung. Sergey also embarks on a tour of the US and Europe with Alisa Weilerstein and Inon Barnaton with a programme titled "Transfigured Nights" featuring the music of Beethoven, Schoenberg and Shostakovich.

The Brahms CD was released in June 2013 on Naïve Classique. Sergey's discography on the label also includes the Sibelius and Khachaturian concerti with Sinfonia Varsovia and Emmanuel Krivine, both Shostakovich concerti with the Orchestre National de France and Kurt Masur, a recording of the Shostakovich and Franck sonatas for violin and piano, and the complete Sonatas and Partitas for solo violin by J.S. Bach.

In 2015 Sergey and Lusine released the album My Armenia, a disc of Armenian music from Komitas till Mirzoyan, which is dedicated to the 100th Commemoration of the Armenian Genocide.

Sergey plays the 1740 "Ysaÿe" Guarneri del Gesu violin on kind loan from the Nippon Music Foundation.