The outstanding Armenian conductor Eduard Topchjan studied violin at the Yerevan Conservatory and went on to study conducting with the prominent Armenian conductor Ohan Durian, followed by valuable consultations from Sir George Solti, Claudio Abbado and Nello Santi.

In 1991 Eduard Topchjan founded the Serenade Chamber Orchestra which soon became the most promising orchestra in Armenia and shortly afterwards it build up a fine international reputation, winning prizes at various prestigious competitions and releasing highly acclaimed CDs with several labels. Topchjan toured Europe regularly with the Serenade, appearing in more than 700 concerts.

Eduard Topchjan made his début with the Armenian National Philharmonic Orchestra in 2000. That same year he was appointed Artistic Director and Principal Conductor of the ANPO and began successful appearances with the ANPO in Armenia and abroad. Maestro Topchjan earned much praise from the critics and the audience for his unique interpretations of the main symphonic and contemporary music repertoire.

Eduard Topchjan is especially known for his wide-ranging repertoire, where besides the symphonic works are included the operas. Amon the operas he has conducted are: Il Barbiere di Siviglia, Aida, Simon Boccanegra, Otello, Rigoletto, Il Tabarro; Madama Butterfly, Turandot, Tosca, La Boheme, Cavalleria Rusticana, I Pagliacci, Eugene Onegin, and others.

Eduard Topchjan has appeared with such clebrated artists as Placido Domingo, Pinchas Zukerman, Renato Bruson, Giuseppe Giacomini, Vladimir Chernov, Vincenzo La Scola, Raina Kabaivanska, Mischa Maisky, Natalia Gutman, Steven Isserlis, David Geringas, Yuri Bashmet, Kim Kashkashian, Diemut Poppen, Emmanuel Pahud, Tibor Varga, Radovan Vlatkovic, Sergei Nakariakov, Boris Berezovsky, Sergey Khachatryan, Julia Fischer, Isabelle Faust, Daishin Kashimoto, Sergei Babayan, Konstantin Lifschitz, François-Joël Thiollier, Paul Mayer, Jana Bouskova, Narek Hakhnazaryan, Alexei Lyubimov, Bernd Glemser, Bernard Ringeissen, Massimo Mercelli, Anton Sorokow, François-Frédéric Guy, Vag Papian, Mario Brunello, Kirill Gerstein, Kolja Blacher, Sergei Krylov, Fabio Zanon, Simon Trpceski, Alexander Chaushian and many others.